Reference: Winey M (1996) Keeping the centrosome cycle on track. Genome stability. Curr Biol 6(8):962-4

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Abstract


The protein kinase Mps1 and p53 both function in centrosome duplication and the spindle cell-cycle checkpoint. Defects in these functions can be potent sources of genomic instability by allowing mitosis to proceed with aberrant mitotic spindles.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S. | Review
Authors
Winey M
Review For
MPS1