Neupert W (2015)

Abstract

Mitochondria are the central hub of key cellular processes such as energy conversion, cell signaling, cell cycle regulation and cell differentiation. Therefore, in particular, mitochondrial biogenesis and protein translocation have been the focus of intense research for now nearly half a century. In spite of remarkable progress the field has made, many of the proposed mechanisms remain controversial and none of the translocation pathways is yet understood at the high-resolution level. In this context, the present article is intended to identify and discuss current major open questions and unresolved issues in the field in hope that it will stimulate and engage the pursuit of current efforts and expose new directions.

PMID: 25676309
DOI full text
PubMed
PubTator

Download Citation (.nbib)

Reference Type: Journal Article | Research Support, Non-U.S. Gov't
Authors: Neupert W
Primary Lit For
Additional Lit For
Review For: TIM17 | SDH3 | COX18 | TOM20 | FIS1 | TIM13 | TIM54 | SAM35 | OXA1 | TIM44 | TIM9 | ... Show all

Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; to filter the table by a specific experiment type, type a keyword into the Filter box (for example, “microarray”); download this table as a .txt file using the Download button or click Analyze to further view and analyze the list of target genes using GO Term Finder, GO Slim Mapper, or SPELL.

Interaction Annotations