Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
3 entries for 2 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
---|---|---|---|---|---|---|---|
KIN28 | autophagy: absent | classical genetics | repressible Allele: kin28-AID | Other | Media: nitrogen starvation Details: block in autophagy indicated by defective delivery of pho8Δ60 to the vacuole | Zhu J, et al. (2016) PMID:26567215 | |
KIN28 | protein/peptide accumulation: decreased Reporter: Atg29-2GFP | classical genetics | repressible Allele: kin28-AID | Other | Media: nitrogen starvation Details: substantial reduction in the levels of Atg29p | Zhu J, et al. (2016) PMID:26567215 | |
KIN28 | protein/peptide accumulation: decreased Reporter: Atg5-2GFP | classical genetics | repressible Allele: kin28-AID | Other | Media: nitrogen starvation Details: reduction in the levels of free Atg5p | Zhu J, et al. (2016) PMID:26567215 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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