Complex: SAGA complex
Macromolecular complex annotations are imported from the Complex Portal. These annotations have been derived from physical molecular interaction evidence extracted from the literature and cross-referenced in the entry, or by curator inference from information on homologs in closely related species or by inference from scientific background.
- Curated by
- IntAct
- ComplexAc
- CPX-656
- Systematic Name
- ADA2:ADA3:CHD1:GCN5:HFI1:SGF11:SGF29:SGF73:SPT20:SPT3:SPT7:SPT8:SUS1:TAF10:TAF12:TAF5:TAF6:TAF9:TRA1:UBP8
- SGD ID
- SGD:S000217881
- Aliases
- ADA2-ADA3-CHD1-GCN5-ADA1-SGF11-SGF29-SGF73-ADA5-SPT3-SPT7-SPT8-SUS1-TAF10-TAF12-TAF5-TAF6-TAF9-TRA1-UBP8 complex ; Something about silencing complex ; Spt-Ada-Gcn5 acetyltransferase complex
Complex Diagram
This diagram displays the protein subunits (blue) of the complex and how they interact with each other. Interactions with other relevant participants such as small molecules (purple), sub-complexes (yellow), and other subunits (red) are also shown. If a participant appears in the diagram with no lines connected to it, then its specific interactions with other participants are currently unknown.
Subunits
This table lists all participants of the complex (proteins, small molecules, nucleic acids, etc.) and their respective stoichiometry. A brief description is also provided for each participant in the table.
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| Subunit | Description | Stoichiometry |
|---|
Gene Ontology
Gene Ontology (GO) terms that describe the function of a complex, the biological process in which it participates, or its cellular location. Click on a term for its definition and other objects annotated to that term.
- Molecular Function
-
- histone acetyltransferase activity
- thiol-dependent ubiquitin-specific protease activity
- Biological Process
-
- histone acetylation
- histone deubiquitination
- regulation of transcription by RNA polymerase II
- Cellular Component
-
- SAGA complex
Shared Annotations
This diagram displays Gene Ontology terms (green) and subunits (blue) that are shared between the given macromolecular complex (black) and other yeast complexes (yellow). The shared GO terms or subunits can be visualized separately using the radio button at the bottom of the graph. Note: No diagram is shown ("No shared annotations") if there are less than 2 shared annotations (either GO terms or subunits of other complexes) between this complex and any other complexes.
References
List of references used specifically to curate the information on this page.
- Pray-Grant MG, et al. (2005) Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation. Nature 433(7024):434-8 PMID: 15647753
- Rodríguez-Navarro S, et al. (2004) Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery. Cell 116(1):75-86 PMID: 14718168
- Wu PY, et al. (2004) Molecular architecture of the S. cerevisiae SAGA complex. Mol Cell 15(2):199-208 PMID: 15260971
- Sterner DE, et al. (2002) SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription. Proc Natl Acad Sci U S A 99(18):11622-7 PMID: 12186975
- Pérez-Martín J (1999) Chromatin and transcription in Saccharomyces cerevisiae. FEMS Microbiol Rev 23(4):503-23 PMID: 10422263