Primary Literature
TEXT HERE
- Breckel CA, et al. (2024) Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1. Sci Rep 14(1):2048 PMID: 38267508
- Bartle L, et al. (2022) Maturation and shuttling of the yeast telomerase RNP: assembling something new using recycled parts. Curr Genet 68(1):3-14 PMID: 34476547
- Lange A, et al. (2020) Dissecting the roles of Cse1 and Nup2 in classical NLS-cargo release in vivo. Traffic 21(10):622-635 PMID: 32734712
- Swale C, et al. (2020) X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. J Mol Biol 432(10):3353-3359 PMID: 32222384
- Perez AM and Thorner J (2019) Septin-associated proteins Aim44 and Nis1 traffic between the bud neck and the nucleus in the yeast Saccharomyces cerevisiae. Cytoskeleton (Hoboken) 76(1):15-32 PMID: 30341817
- Vera Rodriguez A, et al. (2019) Engineered SUMO/protease system identifies Pdr6 as a bidirectional nuclear transport receptor. J Cell Biol 218(6):2006-2020 PMID: 31023724
- Brandi V, et al. (2018) A comprehensive in silico analysis of huntingtin and its interactome. J Biomol Struct Dyn 36(12):3155-3171 PMID: 28920551
- Li S, et al. (2018) Rtt105 functions as a chaperone for replication protein A to preserve genome stability. EMBO J 37(17) PMID: 30065069
- Oka M and Yoneda Y (2018) Importin α: functions as a nuclear transport factor and beyond. Proc Jpn Acad Ser B Phys Biol Sci 94(7):259-274 PMID: 30078827
- Schütz S, et al. (2018) Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2. Nat Commun 9(1):3669 PMID: 30201955
- Chatterjee K, et al. (2017) Sharing the load: Mex67-Mtr2 cofunctions with Los1 in primary tRNA nuclear export. Genes Dev 31(21):2186-2198 PMID: 29212662
- Hirano H, et al. (2017) Structures of the Karyopherins Kap121p and Kap60p Bound to the Nuclear Pore-Targeting Domain of the SUMO Protease Ulp1p. J Mol Biol 429(2):249-260 PMID: 27939291
- Kimura A, et al. (2016) N-Myristoylation of the Rpt2 subunit of the yeast 26S proteasome is implicated in the subcellular compartment-specific protein quality control system. J Proteomics 130:33-41 PMID: 26344132
- Mitterer V, et al. (2016) Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1. Sci Rep 6:36714 PMID: 27819319
- Reichen C, et al. (2016) Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition. J Mol Biol 428(22):4467-4489 PMID: 27664438
- Virgilio S, et al. (2016) Molecular Components of the Neurospora crassa pH Signaling Pathway and Their Regulation by pH and the PAC-3 Transcription Factor. PLoS One 11(8):e0161659 PMID: 27557053
- Yedidi RS, et al. (2016) Proteasome dynamics between proliferation and quiescence stages of Saccharomyces cerevisiae. Crit Rev Biochem Mol Biol 51(6):497-512 PMID: 27677933
- Burcoglu J, et al. (2015) Nuclear Import of Yeast Proteasomes. Cells 4(3):387-405 PMID: 26262643
- Huang HY and Hopper AK (2015) In vivo biochemical analyses reveal distinct roles of β-importins and eEF1A in tRNA subcellular traffic. Genes Dev 29(7):772-83 PMID: 25838545
- Lokareddy RK, et al. (2015) Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure 23(7):1305-1316 PMID: 26051712
- Yoshihisa T (2015) Nucleocytoplasmic shuttling of tRNAs and implication of the cytosolic Hsp70 system in tRNA import. Nucleus 6(5):339-43 PMID: 26280499
- Chen L and Madura K (2014) Yeast importin-α (Srp1) performs distinct roles in the import of nuclear proteins and in targeting proteasomes to the nucleus. J Biol Chem 289(46):32339-32352 PMID: 25274630
- Enenkel C (2014) Nuclear transport of yeast proteasomes. Biomolecules 4(4):940-55 PMID: 25333764
- Ha SW, et al. (2014) Nuclear import factor Srp1 and its associated protein Sts1 couple ribosome-bound nascent polypeptides to proteasomes for cotranslational degradation. J Biol Chem 289(5):2701-10 PMID: 24338021
- Hawkins C and Friedman KL (2014) Normal telomere length maintenance in Saccharomyces cerevisiae requires nuclear import of the ever shorter telomeres 1 (Est1) protein via the importin alpha pathway. Eukaryot Cell 13(8):1036-50 PMID: 24906415
- Huang HY and Hopper AK (2014) Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport. Mol Biol Cell 25(18):2840-52 PMID: 25057022
- Pack CG, et al. (2014) Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome. Nat Commun 5:3396 PMID: 24598877
- Pang X and Zhou HX (2014) Design rules for selective binding of nuclear localization signals to minor site of importin α. PLoS One 9(3):e91025 PMID: 24609064
- Schütz S, et al. (2014) A RanGTP-independent mechanism allows ribosomal protein nuclear import for ribosome assembly. Elife 3:e03473 PMID: 25144938
- Chu HY and Hopper AK (2013) Genome-wide investigation of the role of the tRNA nuclear-cytoplasmic trafficking pathway in regulation of the yeast Saccharomyces cerevisiae transcriptome and proteome. Mol Cell Biol 33(21) PMID: 23979602
- Garg J, et al. (2013) Conserved Asf1-importin β physical interaction in growth and sexual development in the ciliate Tetrahymena thermophila. J Proteomics 94:311-26 PMID: 24120531
- Keck KM and Pemberton LF (2013) Histone chaperones link histone nuclear import and chromatin assembly. Biochim Biophys Acta 1819(3-4):277-89 PMID: 24459730
- Labokha AA, et al. (2013) Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO J 32(2):204-18 PMID: 23202855
- Lorenzato A, et al. (2013) AKT activation drives the nuclear localization of CSE1L and a pro-oncogenic transcriptional activation in ovarian cancer cells. Exp Cell Res 319(17):2627-36 PMID: 23948303
- Roman N, et al. (2013) Structural characterisation of the nuclear import receptor importin alpha in complex with the bipartite NLS of Prp20. PLoS One 8(12):e82038 PMID: 24339986
- Vasicova P, et al. (2013) Nuclear import of chromatin remodeler Isw1 is mediated by atypical bipartite cNLS and classical import pathway. Traffic 14(2):176-93 PMID: 23121014
- Weberruss MH, et al. (2013) Blm10 facilitates nuclear import of proteasome core particles. EMBO J 32(20):2697-707 PMID: 23982732
- Fernández-Cid A, et al. (2012) Yeast importin-β is required for nuclear import of the Mig2 repressor. BMC Cell Biol 13:31 PMID: 23131016
- Keck KM and Pemberton LF (2012) Histone chaperones link histone nuclear import and chromatin assembly. Biochim Biophys Acta 1819(3-4):277-89 PMID: 22015777
- Peláez R, et al. (2012) Nuclear import of the yeast hexokinase 2 protein requires α/β-importin-dependent pathway. J Biol Chem 287(5):3518-29 PMID: 22157003
- Werner A and Melchior F (2012) SUMO unloads the Kap114 cab. EMBO J 31(11):2439-40 PMID: 22562150
- Hahn S and Schlenstedt G (2011) Importin β-type nuclear transport receptors have distinct binding affinities for Ran-GTP. Biochem Biophys Res Commun 406(3):383-8 PMID: 21329658
- Mehdi AM, et al. (2011) A probabilistic model of nuclear import of proteins. Bioinformatics 27(9):1239-46 PMID: 21372083
- Moutty MC, et al. (2011) Importin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzyme. Mol Biol Cell 22(5):652-60 PMID: 21209321
- Staresincic L, et al. (2011) GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein. J Biol Chem 286(41):35553-35561 PMID: 21844196
- Domingues MN, et al. (2010) The Xanthomonas citri effector protein PthA interacts with citrus proteins involved in nuclear transport, protein folding and ubiquitination associated with DNA repair. Mol Plant Pathol 11(5):663-75 PMID: 20696004
- Forwood JK, et al. (2010) Quantitative structural analysis of importin-β flexibility: paradigm for solenoid protein structures. Structure 18(9):1171-83 PMID: 20826343
- Kappel C, et al. (2010) An unusual hydrophobic core confers extreme flexibility to HEAT repeat proteins. Biophys J 99(5):1596-603 PMID: 20816072
- Kim KY, et al. (2010) Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleocytoplasmic shuttling of the Swi6 transcriptional regulator. Mol Biol Cell 21(9):1609-19 PMID: 20219973
- Lange A, et al. (2010) Expanding the definition of the classical bipartite nuclear localization signal. Traffic 11(3):311-23 PMID: 20028483
- Liu D, et al. (2010) Truncated isoforms of Kap60 facilitate trafficking of Heh2 to the nuclear envelope. Traffic 11(12):1506-18 PMID: 20846261
- Murthi A, et al. (2010) Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae. Mol Biol Cell 21(4):639-49 PMID: 20032305
- Straube K, et al. (2010) Nap1 and Chz1 have separate Htz1 nuclear import and assembly functions. Traffic 11(2):185-97 PMID: 19929865
- Taberner FJ and Igual JC (2010) Yeast karyopherin Kap95 is required for cell cycle progression at Start. BMC Cell Biol 11:47 PMID: 20587033
- Tapia H and Morano KA (2010) Hsp90 nuclear accumulation in quiescence is linked to chaperone function and spore development in yeast. Mol Biol Cell 21(1):63-72 PMID: 19889838
- Arai S, et al. (2009) Cell-cycle independent chromosome condensation in Schizosaccharomyces pombe induced by high hydrostatic pressure treatment. Biosci Biotechnol Biochem 73(9):1956-61 PMID: 19734689
- Araújo-Bazán L, et al. (2009) Importin alpha is an essential nuclear import carrier adaptor required for proper sexual and asexual development and secondary metabolism in Aspergillus nidulans. Fungal Genet Biol 46(6-7):506-15 PMID: 19318129
- Ben-Efraim I, et al. (2009) Karyopherin binding interactions and nuclear import mechanism of nuclear pore complex protein Tpr. BMC Cell Biol 10:74 PMID: 19835572
- Chachami G, et al. (2009) Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7. Biochem Biophys Res Commun 390(2):235-40 PMID: 19788888
- Etxebeste O, et al. (2009) KapI, a non-essential member of the Pse1p/Imp5 karyopherin family, controls colonial and asexual development in Aspergillus nidulans. Microbiology (Reading) 155(Pt 12):3934-3945 PMID: 19729403
- Frey S and Görlich D (2009) FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J 28(17):2554-67 PMID: 19680227
- Kosugi S, et al. (2009) Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs. Proc Natl Acad Sci U S A 106(25):10171-6 PMID: 19520826
- Kosugi S, et al. (2009) Six classes of nuclear localization signals specific to different binding grooves of importin alpha. J Biol Chem 284(1):478-485 PMID: 19001369
- Kroetz MB, et al. (2009) Essential role of nuclear localization for yeast Ulp2 SUMO protease function. Mol Biol Cell 20(8):2196-206 PMID: 19225149
- Levin A, et al. (2009) Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal. Retrovirology 6:112 PMID: 19961612
- Lonhienne TG, et al. (2009) Importin-beta is a GDP-to-GTP exchange factor of Ran: implications for the mechanism of nuclear import. J Biol Chem 284(34):22549-58 PMID: 19549784
- MacKinnon MA, et al. (2009) The Kap60-Kap95 karyopherin complex directly regulates phosphatidylcholine synthesis. J Biol Chem 284(11):7376-84 PMID: 19141610
- Mason DA, et al. (2009) Evolution of the metazoan-specific importin alpha gene family. J Mol Evol 68(4):351-65 PMID: 19308634
- Pulliam KF, et al. (2009) The classical nuclear localization signal receptor, importin-alpha, is required for efficient transition through the G1/S stage of the cell cycle in Saccharomyces cerevisiae. Genetics 181(1):105-18 PMID: 18984568
- Roman N, et al. (2009) Crystallization of the flexible nuclear import receptor importin-beta in the unliganded state. Acta Crystallogr Sect F Struct Biol Cryst Commun 65(Pt 6):625-8 PMID: 19478448
- Shen Z, et al. (2009) Nuclear shuttling of She2p couples ASH1 mRNA localization to its translational repression by recruiting Loc1p and Puf6p. Mol Biol Cell 20(8):2265-75 PMID: 19244342
- Streckfuss-Bömeke K, et al. (2009) Degradation of Saccharomyces cerevisiae transcription factor Gcn4 requires a C-terminal nuclear localization signal in the cyclin Pcl5. Eukaryot Cell 8(4):496-510 PMID: 19218424
- Synowsky SA, et al. (2009) Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes. J Mol Biol 385(4):1300-13 PMID: 19046973
- Zhao G, et al. (2009) An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation. Proc Natl Acad Sci U S A 106(38):16197-202 PMID: 19805280
- Araújo-Bazán L, et al. (2008) NapA and NapB are the Aspergillus nidulans Nap/SET family members and NapB is a nuclear protein specifically interacting with importin alpha. Fungal Genet Biol 45(3):278-91 PMID: 17890114
- Forwood JK, et al. (2008) Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J Mol Biol 383(4):772-82 PMID: 18708071
- Gallardo F, et al. (2008) TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres. EMBO J 27(5):748-57 PMID: 18273059
- Hahn S, et al. (2008) Classical NLS proteins from Saccharomyces cerevisiae. J Mol Biol 379(4):678-94 PMID: 18485366
- Kosugi S, et al. (2008) Design of peptide inhibitors for the importin alpha/beta nuclear import pathway by activity-based profiling. Chem Biol 15(9):940-9 PMID: 18804031
- Lange A, et al. (2008) A PY-NLS nuclear targeting signal is required for nuclear localization and function of the Saccharomyces cerevisiae mRNA-binding protein Hrp1. J Biol Chem 283(19):12926-34 PMID: 18343812
- McLane LM, et al. (2008) The Ty1 integrase protein can exploit the classical nuclear protein import machinery for entry into the nucleus. Nucleic Acids Res 36(13):4317-26 PMID: 18586821
- Patel SS and Rexach MF (2008) Discovering novel interactions at the nuclear pore complex using bead halo: a rapid method for detecting molecular interactions of high and low affinity at equilibrium. Mol Cell Proteomics 7(1):121-31 PMID: 17897934
- Zachariae U and Grubmüller H (2008) Importin-beta: structural and dynamic determinants of a molecular spring. Structure 16(6):906-15 PMID: 18547523
- Blackwell JS, et al. (2007) Mutational analysis of H3 and H4 N termini reveals distinct roles in nuclear import. J Biol Chem 282(28):20142-50 PMID: 17507373
- Frey S and Görlich D (2007) A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes. Cell 130(3):512-23 PMID: 17693259
- Fries T, et al. (2007) A novel conserved nuclear localization signal is recognized by a group of yeast importins. J Biol Chem 282(27):19292-301 PMID: 17485461
- Gardiner FC, et al. (2007) Nucleocytoplasmic trafficking is required for functioning of the adaptor protein Sla1p in endocytosis. Traffic 8(4):347-58 PMID: 17286805
- Holt JE, et al. (2007) Regulation of Nuclear Import During Differentiation; The IMP alpha Gene Family and Spermatogenesis. Curr Genomics 8(5):323-34 PMID: 19384428
- Quan X, et al. (2007) The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress. Biochim Biophys Acta 1773(7):1052-61 PMID: 17544521
- Bakhrat A, et al. (2006) Nuclear import of ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system. J Biol Chem 281(18):12218-26 PMID: 16507575
- Butterfield-Gerson KL, et al. (2006) Importin-beta family members mediate alpharetrovirus gag nuclear entry via interactions with matrix and nucleocapsid. J Virol 80(4):1798-806 PMID: 16439536
- Caesar S, et al. (2006) Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast. Mol Cell Biol 26(8):3170-80 PMID: 16581791
- Goffin L, et al. (2006) The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins. Mol Biol Cell 17(12):5309-23 PMID: 17035634
- Hodel AE, et al. (2006) Nuclear localization signal receptor affinity correlates with in vivo localization in Saccharomyces cerevisiae. J Biol Chem 281(33):23545-56 PMID: 16785238
- Quan X, et al. (2006) The carrier Msn5p/Kap142p promotes nuclear export of the hsp70 Ssa4p and relocates in response to stress. Mol Microbiol 62(2):592-609 PMID: 17020589
- Shibata S, et al. (2006) Exportin-5 orthologues are functionally divergent among species. Nucleic Acids Res 34(17):4711-21 PMID: 16963774
- Zhang Z, et al. (2006) Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein. Proc Natl Acad Sci U S A 103(5):1422-7 PMID: 16432237
- Cook A, et al. (2005) The structure of the nuclear export receptor Cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding. Mol Cell 18(3):355-67 PMID: 15866177
- Hodges JL, et al. (2005) Nuclear import of TFIIB is mediated by Kap114p, a karyopherin with multiple cargo-binding domains. Mol Biol Cell 16(7):3200-10 PMID: 15888545
- Kashyap AK, et al. (2005) Biochemical and genetic characterization of Yra1p in budding yeast. Yeast 22(1):43-56 PMID: 15584090
- Lee SJ, et al. (2005) Structural basis for nuclear import complex dissociation by RanGTP. Nature 435(7042):693-6 PMID: 15864302
- Liu SM and Stewart M (2005) Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p. J Mol Biol 349(3):515-25 PMID: 15878174
- Mosammaparast N, et al. (2005) Modulation of histone deposition by the karyopherin kap114. Mol Cell Biol 25(5):1764-78 PMID: 15713633
- Schaper S, et al. (2005) Nuclear import of the histone acetyltransferase complex SAS-I in Saccharomyces cerevisiae. J Cell Sci 118(Pt 7):1473-84 PMID: 15788653
- Shaheen HH and Hopper AK (2005) Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 102(32):11290-5 PMID: 16040803
- Strahl T, et al. (2005) Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the Golgi and in the nucleus. J Cell Biol 171(6):967-79 PMID: 16365163
- You Z, et al. (2005) ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol Cell Biol 25(13):5363-79 PMID: 15964794
- Belanger KD, et al. (2004) The karyopherin Msn5/Kap142 requires Nup82 for nuclear export and performs a function distinct from translocation in RPA protein import. J Biol Chem 279(42):43530-9 PMID: 15294903
- Chen XQ, et al. (2004) Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis. Yeast 21(6):495-509 PMID: 15116432
- Freedman ND and Yamamoto KR (2004) Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor. Mol Biol Cell 15(5):2276-86 PMID: 15004228
- Greiner M, et al. (2004) The histones H2A/H2B and H3/H4 are imported into the yeast nucleus by different mechanisms. Eur J Cell Biol 83(10):511-20 PMID: 15679097
- Harreman MT, et al. (2004) Regulation of nuclear import by phosphorylation adjacent to nuclear localization signals. J Biol Chem 279(20):20613-21 PMID: 14998990
- Matsuura Y and Stewart M (2004) Structural basis for the assembly of a nuclear export complex. Nature 432(7019):872-7 PMID: 15602554
- Pries R, et al. (2004) Nuclear import of yeast Gcn4p requires karyopherins Srp1p and Kap95p. Mol Genet Genomics 271(3):257-66 PMID: 14648200
- Quan X, et al. (2004) Regulated nuclear accumulation of the yeast hsp70 Ssa4p in ethanol-stressed cells is mediated by the N-terminal domain, requires the nuclear carrier Nmd5p and protein kinase C. FASEB J 18(7):899-901 PMID: 15001563
- Bollman KM, et al. (2003) HASTY, the Arabidopsis ortholog of exportin 5/MSN5, regulates phase change and morphogenesis. Development 130(8):1493-504 PMID: 12620976
- Harreman MT, et al. (2003) The auto-inhibitory function of importin alpha is essential in vivo. J Biol Chem 278(8):5854-63 PMID: 12486120
- Harreman MT, et al. (2003) Characterization of the auto-inhibitory sequence within the N-terminal domain of importin alpha. J Biol Chem 278(24):21361-9 PMID: 12672802
- Leung SW, et al. (2003) Dissection of the karyopherin alpha nuclear localization signal (NLS)-binding groove: functional requirements for NLS binding. J Biol Chem 278(43):41947-53 PMID: 12917403
- Matsuura Y, et al. (2003) Structural basis for Nup2p function in cargo release and karyopherin recycling in nuclear import. EMBO J 22(20):5358-69 PMID: 14532109
- Nikolaev I, et al. (2003) Nuclear import of zinc binuclear cluster proteins proceeds through multiple, overlapping transport pathways. Eukaryot Cell 2(2):209-21 PMID: 12684370
- Ziemienowicz A, et al. (2003) Arabidopsis transportin1 is the nuclear import receptor for the circadian clock-regulated RNA-binding protein AtGRP7. Plant Mol Biol 53(1-2):201-12 PMID: 14756317
- Allemand E, et al. (2002) A conserved Drosophila transportin-serine/arginine-rich (SR) protein permits nuclear import of Drosophila SR protein splicing factors and their antagonist repressor splicing factor 1. Mol Biol Cell 13(7):2436-47 PMID: 12134081
- Allen NP, et al. (2002) Deciphering networks of protein interactions at the nuclear pore complex. Mol Cell Proteomics 1(12):930-46 PMID: 12543930
- Asakawa K and Toh-e A (2002) A defect of Kap104 alleviates the requirement of mitotic exit network gene functions in Saccharomyces cerevisiae. Genetics 162(4):1545-56 PMID: 12524331
- Bayliss R, et al. (2002) GLFG and FxFG nucleoporins bind to overlapping sites on importin-beta. J Biol Chem 277(52):50597-606 PMID: 12372823
- Bayliss R, et al. (2002) Structural basis for the interaction between NTF2 and nucleoporin FxFG repeats. EMBO J 21(12):2843-53 PMID: 12065398
- Chua G, et al. (2002) The sal3(+) gene encodes an importin-beta implicated in the nuclear import of Cdc25 in Schizosaccharomyces pombe. Genetics 162(2):689-703 PMID: 12399381
- Jaquenoud M, et al. (2002) Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1). EMBO J 21(23):6515-26 PMID: 12456658
- Lehmann A, et al. (2002) 20 S proteasomes are imported as precursor complexes into the nucleus of yeast. J Mol Biol 317(3):401-13 PMID: 11922673
- Miyamoto Y, et al. (2002) Importin alpha can migrate into the nucleus in an importin beta- and Ran-independent manner. EMBO J 21(21):5833-42 PMID: 12411501
- Mosammaparast N, et al. (2002) A role for nucleosome assembly protein 1 in the nuclear transport of histones H2A and H2B. EMBO J 21(23):6527-38 PMID: 12456659
- Mosammaparast N, et al. (2002) Pathways mediating the nuclear import of histones H3 and H4 in yeast. J Biol Chem 277(1):862-8 PMID: 11694505
- Shirley RL, et al. (2002) Nuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeast. Genetics 161(4):1465-82 PMID: 12196393
- Stade K, et al. (2002) A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast. J Biol Chem 277(51):49554-61 PMID: 12393908
- Akhtar N, et al. (2001) Functional analysis of the yeast Ran exchange factor Prp20p: in vivo evidence for the RanGTP gradient model. Mol Genet Genomics 265(5):851-64 PMID: 11523802
- Allen NP, et al. (2001) Proteomic analysis of nucleoporin interacting proteins. J Biol Chem 276(31):29268-74 PMID: 11387327
- Catimel B, et al. (2001) Biophysical characterization of interactions involving importin-alpha during nuclear import. J Biol Chem 276(36):34189-98 PMID: 11448961
- Chughtai ZS, et al. (2001) Starvation promotes nuclear accumulation of the hsp70 Ssa4p in yeast cells. J Biol Chem 276(23):20261-6 PMID: 11279056
- Delahodde A, et al. (2001) Pse1/Kap121-dependent nuclear localization of the major yeast multidrug resistance (MDR) transcription factor Pdr1. Mol Microbiol 39(2):304-12 PMID: 11136452
- Franke J, et al. (2001) Evidence for a nuclear passage of nascent polypeptide-associated complex subunits in yeast. J Cell Sci 114(Pt 14):2641-8 PMID: 11683391
- Geles KG and Adam SA (2001) Germline and developmental roles of the nuclear transport factor importin alpha3 in C. elegans. Development 128(10):1817-30 PMID: 11311162
- Hood JK, et al. (2001) The Saccharomyces cerevisiae cyclin Clb2p is targeted to multiple subcellular locations by cis- and trans-acting determinants. J Cell Sci 114(Pt 3):589-97 PMID: 11171327
- Isoyama T, et al. (2001) Nuclear import of the yeast AP-1-like transcription factor Yap1p is mediated by transport receptor Pse1p, and this import step is not affected by oxidative stress. J Biol Chem 276(24):21863-9 PMID: 11274141
- Künzler M and Hurt E (2001) Targeting of Ran: variation on a common theme? J Cell Sci 114(Pt 18):3233-41 PMID: 11591812
- Künzler M, et al. (2001) Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects. Genetics 157(3):1089-105 PMID: 11238397
- Marelli M, et al. (2001) The dynamics of karyopherin-mediated nuclear transport. Biochem Cell Biol 79(5):603-12 PMID: 11716302
- Maurer P, et al. (2001) The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast Ran binding protein 1 (Yrb1p). Mol Biol Cell 12(3):539-49 PMID: 11251069
- Mink M, et al. (2001) A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 74(2):234-44 PMID: 11386760
- Moore JD (2001) The Ran-GTPase and cell-cycle control. Bioessays 23(1):77-85 PMID: 11135312
- Mosammaparast N, et al. (2001) Nuclear import of histone H2A and H2B is mediated by a network of karyopherins. J Cell Biol 153(2):251-62 PMID: 11309407
- Sagermann M, et al. (2001) Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 98(13):7134-9 PMID: 11416198
- Ström AC and Weis K (2001) Importin-beta-like nuclear transport receptors. Genome Biol 2(6):REVIEWS3008 PMID: 11423015
- Yen YM, et al. (2001) Nuclear localization of the Saccharomyces cerevisiae HMG protein NHP6A occurs by a Ran-independent nonclassical pathway. Traffic 2(7):449-64 PMID: 11422939
- Bayliss R, et al. (2000) Crystallization and initial X-ray diffraction characterization of complexes of FxFG nucleoporin repeats with nuclear transport factors. J Struct Biol 131(3):240-7 PMID: 11052897
- Bayliss R, et al. (2000) Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell 102(1):99-108 PMID: 10929717
- Conti E and Kuriyan J (2000) Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Structure 8(3):329-38 PMID: 10745017
- Damelin M and Silver PA (2000) Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex. Mol Cell 5(1):133-40 PMID: 10678175
- Fanara P, et al. (2000) Quantitative analysis of nuclear localization signal (NLS)-importin alpha interaction through fluorescence depolarization. Evidence for auto-inhibitory regulation of NLS binding. J Biol Chem 275(28):21218-23 PMID: 10806202
- Fontes MR, et al. (2000) Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha. J Mol Biol 297(5):1183-94 PMID: 10764582
- Grosshans H, et al. (2000) Review: transport of tRNA out of the nucleus-direct channeling to the ribosome? J Struct Biol 129(2-3):288-94 PMID: 10806079
- Hood JK, et al. (2000) Nup2p is located on the nuclear side of the nuclear pore complex and coordinates Srp1p/importin-alpha export. J Cell Sci 113 ( Pt 8):1471-80 PMID: 10725229
- Komeili A, et al. (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78 PMID: 11076970
- Lai MC, et al. (2000) A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins. J Biol Chem 275(11):7950-7 PMID: 10713112
- Lee SJ, et al. (2000) The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport. J Mol Biol 302(1):251-64 PMID: 10964573
- Lucas M, et al. (2000) Sequence analysis of two cosmids from Schizosaccharomyces pombe chromosome III. Yeast 16(16):1519-26 PMID: 11113974
- Pan X, et al. (2000) Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p. Mol Biol Cell 11(7):2445-57 PMID: 10888680
- Petersen C, et al. (2000) Random mutagenesis and functional analysis of the Ran-binding protein, RanBP1. J Biol Chem 275(6):4081-91 PMID: 10660567
- Plafker SM and Macara IG (2000) Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2. EMBO J 19(20):5502-13 PMID: 11032817
- Quimby BB, et al. (2000) The mechanism of ran import into the nucleus by nuclear transport factor 2. J Biol Chem 275(37):28575-82 PMID: 10889207
- Shakulov VR, et al. (2000) Interaction of yeast importin alpha with the NLS of prothymosin alpha is insufficient to trigger nuclear uptake of cargos. Biochem Biophys Res Commun 274(2):548-52 PMID: 10913375
- Shulga N, et al. (2000) Yeast nucleoporins involved in passive nuclear envelope permeability. J Cell Biol 149(5):1027-38 PMID: 10831607
- Solsbacher J, et al. (2000) Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha. Mol Cell Biol 20(22):8468-79 PMID: 11046143
- Tabb MM, et al. (2000) Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol 20(16):6062-73 PMID: 10913188
- Zhao Y and Elder RT (2000) Yeast perspectives on HIV-1 VPR. Front Biosci 5:D905-16 PMID: 11102318
- Booth JW, et al. (1999) The yeast nucleoporin Nup2p is involved in nuclear export of importin alpha/Srp1p. J Biol Chem 274(45):32360-7 PMID: 10542277
- Chan CK and Jans DA (1999) Synergy of importin alpha recognition and DNA binding by the yeast transcriptional activator GAL4. FEBS Lett 462(1-2):221-4 PMID: 10580123
- Chook YM and Blobel G (1999) Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp. Nature 399(6733):230-7 PMID: 10353245
- Cingolani G, et al. (1999) Structure of importin-beta bound to the IBB domain of importin-alpha. Nature 399(6733):221-9 PMID: 10353244
- DeVit MJ and Johnston M (1999) The nuclear exportin Msn5 is required for nuclear export of the Mig1 glucose repressor of Saccharomyces cerevisiae. Curr Biol 9(21):1231-41 PMID: 10556086
- Groves MR, et al. (1999) The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 96(1):99-110 PMID: 9989501
- Hu W and Jans DA (1999) Efficiency of importin alpha/beta-mediated nuclear localization sequence recognition and nuclear import. Differential role of NTF2. J Biol Chem 274(22):15820-7 PMID: 10336485
- Kent HM, et al. (1999) Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import. J Mol Biol 289(3):565-77 PMID: 10356329
- Kobe B (1999) Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha. Nat Struct Biol 6(4):388-97 PMID: 10201409
- Köhler M, et al. (1999) Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import. Mol Cell Biol 19(11):7782-91 PMID: 10523667
- Lee DC and Aitchison JD (1999) Kap104p-mediated nuclear import. Nuclear localization signals in mRNA-binding proteins and the role of Ran and Rna. J Biol Chem 274(41):29031-7 PMID: 10506153
- Liu Y, et al. (1999) A Crm1p-independent nuclear export path for the mRNA-associated protein, Npl3p/Mtr13p. Proc Natl Acad Sci U S A 96(12):6739-44 PMID: 10359782
- Morehouse H, et al. (1999) The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein. Proc Natl Acad Sci U S A 96(22):12542-7 PMID: 10535958
- Nanduri J, et al. (1999) An unexpected link between the secretory path and the organization of the nucleus. J Biol Chem 274(47):33785-9 PMID: 10559272
- Pemberton LF, et al. (1999) Nuclear import of the TATA-binding protein: mediation by the karyopherin Kap114p and a possible mechanism for intranuclear targeting. J Cell Biol 145(7):1407-17 PMID: 10385521
- Seedorf M, et al. (1999) Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase. Mol Cell Biol 19(2):1547-57 PMID: 9891088
- Timmers AC, et al. (1999) Nuclear and nucleolar localization of Saccharomyces cerevisiae ribosomal proteins S22 and S25. FEBS Lett 452(3):335-40 PMID: 10386617
- Vetter IR, et al. (1999) Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. Nature 398(6722):39-46 PMID: 10078529
- Vetter IR, et al. (1999) Structural view of the Ran-Importin beta interaction at 2.3 A resolution. Cell 97(5):635-46 PMID: 10367892
- Conti E, et al. (1998) Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell 94(2):193-204 PMID: 9695948
- Ferrigno P, et al. (1998) Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. EMBO J 17(19):5606-14 PMID: 9755161
- Fleckenstein D, et al. (1998) Yel013p (Vac8p), an armadillo repeat protein related to plakoglobin and importin alpha is associated with the yeast vacuole membrane. J Cell Sci 111 ( Pt 20):3109-18 PMID: 9739084
- Hellmuth K, et al. (1998) Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA. Mol Cell Biol 18(11):6374-86 PMID: 9774653
- Hood JK and Silver PA (1998) Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae. J Biol Chem 273(52):35142-6 PMID: 9857050
- Iwasaki T, et al. (1998) A novel importin alpha from rice, a component involved in the process of nuclear protein transport. FEBS Lett 428(3):259-62 PMID: 9654145
- Kaffman A, et al. (1998) Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121. Genes Dev 12(17):2673-83 PMID: 9732266
- Kaffman A, et al. (1998) The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature 396(6710):482-6 PMID: 9853758
- Künzler M and Hurt EC (1998) Cse1p functions as the nuclear export receptor for importin alpha in yeast. FEBS Lett 433(3):185-90 PMID: 9744791
- Li S, et al. (1998) Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs. J Biol Chem 273(11):6183-9 PMID: 9497340
- Pan X and Goldfarb DS (1998) YEB3/VAC8 encodes a myristylated armadillo protein of the Saccharomyces cerevisiae vacuolar membrane that functions in vacuole fusion and inheritance. J Cell Sci 111 ( Pt 15):2137-47 PMID: 9664035
- Shoji K, et al. (1998) Cloning of a cDNA encoding an importin-alpha and down-regulation of the gene by light in rice leaves. Gene 212(2):279-86 PMID: 9678973
- Solsbacher J, et al. (1998) Cse1p is involved in export of yeast importin alpha from the nucleus. Mol Cell Biol 18(11):6805-15 PMID: 9774694
- Taura T, et al. (1998) A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export. Proc Natl Acad Sci U S A 95(13):7427-32 PMID: 9636166
- Truant R, et al. (1998) Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein. Mol Cell Biol 18(3):1449-58 PMID: 9488461
- Vodicka MA, et al. (1998) HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection. Genes Dev 12(2):175-85 PMID: 9436978
- Fornerod M, et al. (1997) The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. EMBO J 16(4):807-16 PMID: 9049309
- Görlich D, et al. (1997) A novel class of RanGTP binding proteins. J Cell Biol 138(1):65-80 PMID: 9214382
- Kutay U, et al. (1997) Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor. Cell 90(6):1061-71 PMID: 9323134
- Lounsbury KM and Macara IG (1997) Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta. J Biol Chem 272(1):551-5 PMID: 8995296
- Malik HS, et al. (1997) Evolutionary specialization of the nuclear targeting apparatus. Proc Natl Acad Sci U S A 94(25):13738-42 PMID: 9391096
- Neville M, et al. (1997) The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export. Curr Biol 7(10):767-75 PMID: 9368759
- Rosenblum JS, et al. (1997) A nuclear import pathway for a protein involved in tRNA maturation. J Cell Biol 139(7):1655-61 PMID: 9412461
- Schlenstedt G, et al. (1997) Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus. EMBO J 16(20):6237-49 PMID: 9321403
- Seedorf M and Silver PA (1997) Importin/karyopherin protein family members required for mRNA export from the nucleus. Proc Natl Acad Sci U S A 94(16):8590-5 PMID: 9238021
- Seki T, et al. (1997) Cloning of a cDNA encoding a novel importin-alpha homologue, Qip1: discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQL. Biochem Biophys Res Commun 234(1):48-53 PMID: 9168958
- Stade K, et al. (1997) Exportin 1 (Crm1p) is an essential nuclear export factor. Cell 90(6):1041-50 PMID: 9323132
- Takeda S, et al. (1997) Isolation and mapping of karyopherin alpha 3 (KPNA3), a human gene that is highly homologous to genes encoding Xenopus importin, yeast SRP1 and human RCH1. Cytogenet Cell Genet 76(1-2):87-93 PMID: 9154134
- Clarkson WD, et al. (1996) Separate binding sites on nuclear transport factor 2 (NTF2) for GDP-Ran and the phenylalanine-rich repeat regions of nucleoporins p62 and Nsp1p. J Mol Biol 263(4):517-24 PMID: 8918934
- Görlich D, et al. (1996) Importin provides a link between nuclear protein import and U snRNA export. Cell 87(1):21-32 PMID: 8858145
- Görlich D, et al. (1996) Identification of different roles for RanGDP and RanGTP in nuclear protein import. EMBO J 15(20):5584-94 PMID: 8896452
- Koepp DM, et al. (1996) Dynamic localization of the nuclear import receptor and its interactions with transport factors. J Cell Biol 133(6):1163-76 PMID: 8682856
- Nakashima N, et al. (1996) Putative GTPase Gtr1p genetically interacts with the RanGTPase cycle in Saccharomyces cerevisiae. J Cell Sci 109 ( Pt 9):2311-8 PMID: 8886981
- Nakielny S, et al. (1996) Transportin: nuclear transport receptor of a novel nuclear protein import pathway. Exp Cell Res 229(2):261-6 PMID: 8986607
- Prieve MG, et al. (1996) The nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteins. J Biol Chem 271(13):7654-8 PMID: 8631802
- Azuma Y, et al. (1995) Isolation of a yeast protein kinase that is activated by the protein encoded by SRP1 (Srp1p) and phosphorylates Srp1p complexed with nuclear localization signal peptides. Proc Natl Acad Sci U S A 92(11):5159-63 PMID: 7761467
- Enenkel C, et al. (1995) Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes. J Biol Chem 270(28):16499-502 PMID: 7622450
- Küssel P and Frasch M (1995) Pendulin, a Drosophila protein with cell cycle-dependent nuclear localization, is required for normal cell proliferation. J Cell Biol 129(6):1491-507 PMID: 7790350
- Loeb JD, et al. (1995) The yeast nuclear import receptor is required for mitosis. Proc Natl Acad Sci U S A 92(17):7647-51 PMID: 7644471