Primary Literature
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- Fu X, et al. (2022) Identification of transient intermediates during spliceosome activation by single molecule fluorescence microscopy. Proc Natl Acad Sci U S A 119(48):e2206815119 PMID: 36417433
- Montemayor EJ, et al. (2018) Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun 9(1):1749 PMID: 29717126
- Roth AJ, et al. (2018) Defining essential elements and genetic interactions of the yeast Lsm2-8 ring and demonstration that essentiality of Lsm2-8 is bypassed via overexpression of U6 snRNA or the U6 snRNP subunit Prp24. RNA 24(6):853-864 PMID: 29615482
- Didychuk AL, et al. (2017) Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nat Commun 8(1):497 PMID: 28887445
- Didychuk AL, et al. (2016) Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly. Nucleic Acids Res 44(3):1398-410 PMID: 26673715
- Rigo N, et al. (2015) Protein localisation by electron microscopy reveals the architecture of the yeast spliceosomal B complex. EMBO J 34(24):3059-73 PMID: 26582754
- Rodgers ML, et al. (2015) Rapid isolation and single-molecule analysis of ribonucleoproteins from cell lysate by SNAP-SiMPull. RNA 21(5):1031-41 PMID: 25805862
- Santos K, et al. (2015) Crystallization and biochemical characterization of the human spliceosomal Aar2-Prp8(RNaseH) complex. Acta Crystallogr F Struct Biol Commun 71(Pt 11):1421-8 PMID: 26527271
- Zhang L, et al. (2015) Brr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding. Nucleic Acids Res 43(6):3286-97 PMID: 25670679
- Montemayor EJ, et al. (2014) Core structure of the U6 small nuclear ribonucleoprotein at 1.7-Å resolution. Nat Struct Mol Biol 21(6):544-51 PMID: 24837192
- Zhou L, et al. (2014) Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature 506(7486):116-20 PMID: 24240276
- Chen HC and Cheng SC (2012) Functional roles of protein splicing factors. Biosci Rep 32(4):345-59 PMID: 22762203
- Fabrizio P, et al. (2009) The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell 36(4):593-608 PMID: 19941820
- Hage R, et al. (2009) A targeted bypass screen identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for stable U1 snRNP/Pre-mRNA interaction. Mol Cell Biol 29(14):3941-52 PMID: 19451230
- Häcker I, et al. (2008) Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy. Nat Struct Mol Biol 15(11):1206-12 PMID: 18953335
- Karaduman R, et al. (2008) Structure of yeast U6 snRNPs: arrangement of Prp24p and the LSm complex as revealed by electron microscopy. RNA 14(12):2528-37 PMID: 18971323
- Sapra AK, et al. (2008) The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis. Biochem J 416(3):365-74 PMID: 18691155
- Spiller MP, et al. (2007) The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA. Nucleic Acids Res 35(3):923-9 PMID: 17251193
- Boon KL, et al. (2006) Yeast ntr1/spp382 mediates prp43 function in postspliceosomes. Mol Cell Biol 26(16):6016-23 PMID: 16880513
- Chen CH, et al. (2006) Functional links between the Prp19-associated complex, U4/U6 biogenesis, and spliceosome recycling. RNA 12(5):765-74 PMID: 16540691
- Combs DJ, et al. (2006) Prp43p is a DEAH-box spliceosome disassembly factor essential for ribosome biogenesis. Mol Cell Biol 26(2):523-34 PMID: 16382144
- Karaduman R, et al. (2006) RNA structure and RNA-protein interactions in purified yeast U6 snRNPs. J Mol Biol 356(5):1248-62 PMID: 16410014
- Liang XH and Fournier MJ (2006) The helicase Has1p is required for snoRNA release from pre-rRNA. Mol Cell Biol 26(20):7437-50 PMID: 16908538
- Kwan SS and Brow DA (2005) The N- and C-terminal RNA recognition motifs of splicing factor Prp24 have distinct functions in U6 RNA binding. RNA 11(5):808-20 PMID: 15811912
- Bell M, et al. (2002) p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor. EMBO J 21(11):2724-35 PMID: 12032085
- Makarova OV, et al. (2002) Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing. EMBO J 21(5):1148-57 PMID: 11867543
- Mougin A, et al. (2002) Direct probing of RNA structure and RNA-protein interactions in purified HeLa cell's and yeast spliceosomal U4/U6.U5 tri-snRNP particles. J Mol Biol 317(5):631-49 PMID: 11955014
- Rader SD and Guthrie C (2002) A conserved Lsm-interaction motif in Prp24 required for efficient U4/U6 di-snRNP formation. RNA 8(11):1378-92 PMID: 12458792
- Ryan DE and Abelson J (2002) The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly. RNA 8(8):997-1010 PMID: 12212854
- Ryan DE, et al. (2002) The 5' and 3' domains of yeast U6 snRNA: Lsm proteins facilitate binding of Prp24 protein to the U6 telestem region. RNA 8(8):1011-33 PMID: 12212846
- Stevens SW, et al. (2002) Composition and functional characterization of the yeast spliceosomal penta-snRNP. Mol Cell 9(1):31-44 PMID: 11804584
- Pannone BK, et al. (2001) Multiple functional interactions between components of the Lsm2-Lsm8 complex, U6 snRNA, and the yeast La protein. Genetics 158(1):187-96 PMID: 11333229
- Stevens SW, et al. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7(11):1543-53 PMID: 11720284
- Makarov EM, et al. (2000) The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. J Mol Biol 298(4):567-75 PMID: 10788320
- Xue D, et al. (2000) U snRNP assembly in yeast involves the La protein. EMBO J 19(7):1650-60 PMID: 10747032
- Achsel T, et al. (1999) A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO J 18(20):5789-802 PMID: 10523320
- Bracken AP and Bond U (1999) Reassembly and protection of small nuclear ribonucleoprotein particles by heat shock proteins in yeast cells. RNA 5(12):1586-96 PMID: 10606269
- Lygerou Z, et al. (1999) A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing. Mol Cell Biol 19(3):2008-20 PMID: 10022888
- Mayes AE, et al. (1999) Characterization of Sm-like proteins in yeast and their association with U6 snRNA. EMBO J 18(15):4321-31 PMID: 10428970
- Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31 PMID: 10377396
- Vidal VP, et al. (1999) Characterization of U6 snRNA-protein interactions. RNA 5(11):1470-81 PMID: 10580475
- Ayadi L, et al. (1998) Functional and structural characterization of the prp3 binding domain of the yeast prp4 splicing factor. J Mol Biol 284(3):673-87 PMID: 9826507
- Pannone BK, et al. (1998) A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts. EMBO J 17(24):7442-53 PMID: 9857199
- Raghunathan PL and Guthrie C (1998) A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles. Science 279(5352):857-60 PMID: 9452384
- Raghunathan PL and Guthrie C (1998) RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr Biol 8(15):847-55 PMID: 9705931
- Anthony JG, et al. (1997) The yeast Prp3 protein is a U4/U6 snRNP protein necessary for integrity of the U4/U6 snRNP and the U4/U6.U5 tri-snRNP. RNA 3(10):1143-52 PMID: 9326489
- Horowitz DS, et al. (1997) A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs. RNA 3(12):1374-87 PMID: 9404889
- Lauber J, et al. (1997) The human U4/U6 snRNP contains 60 and 90kD proteins that are structurally homologous to the yeast splicing factors Prp4p and Prp3p. RNA 3(8):926-41 PMID: 9257651
- Ruby SW (1997) Dynamics of the U1 small nuclear ribonucleoprotein during yeast spliceosome assembly. J Biol Chem 272(28):17333-41 PMID: 9211871
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- Séraphin B (1995) Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs. EMBO J 14(9):2089-98 PMID: 7744014
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