VRP1 / YLR337C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

VRP1/YLR337C is a non-essential gene; null mutants are viable but exhibit a range of phenotypes including decreased bipolar budding pattern, abnormal cell shape, increased chitin deposition, decreased endocytosis, abnormal filamentous growth, decreased growth rate in the exponential phase, decreased hyperosmotic stress resistance, increased metal resistance, abnormal vacuolar morphology, increased cell size, decreased chronological lifespan, abnormal colony appearance, decreased competitive fitness, decreased desiccation resistance, decreased fermentative growth rate, increased heat sensitivity, increased killer toxin resistance, decreased mitotic recombination, decreased oxidative stress resistance, absent respiratory growth, abnormal sporulation, decreased stress resistance, decreased toxin resistance, decreased utilization of carbon source, and decreased vegetative growth rate. Conditional mutants show decreased endocytosis and increased heat sensitivity. Overexpression of VRP1 results in increased invasive growth and decreased vegetative growth rate.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources