ORM2 / YLR350W Homology
- Standard Name
- ORM2 1
- Systematic Name
- YLR350W
- SGD ID
- SGD:S000004342
- Feature Type
- ORF , Verified
- Description
- Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; protein abundance increases in response to DNA replication stress; ORM2 has a paralog, ORM1, that arose from the whole genome duplication 1 2 3 4 5
- Paralog
- ORM1 4
- Comparative Info
-
Homologs
Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.
15 entries for 15 homologsIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
| Species | Gene ID | Gene name | Source |
|---|---|---|---|
| Danio rerio | ZFIN:ZDB-GENE-060331-113 | ormdl2 | Alliance |
| Danio rerio | ZFIN:ZDB-GENE-041010-190 | ormdl3 | Alliance |
| Danio rerio | ZFIN:ZDB-GENE-030616-529 | ormdl1 | Alliance |
| Drosophila melanogaster | FB:FBgn0037110 | ORMDL | Alliance |
| Homo sapiens | HGNC:16036 | ORMDL1 | Alliance |
| Homo sapiens | HGNC:16038 | ORMDL3 | Alliance |
| Homo sapiens | HGNC:16037 | ORMDL2 | Alliance |
| Mus musculus | MGI:1913862 | Ormdl3 | Alliance |
| Mus musculus | MGI:2181669 | Ormdl1 | Alliance |
| Mus musculus | MGI:1914094 | Ormdl2 | Alliance |
Functional Complementation
Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).
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| Complement ID | Locus ID | Gene | Species | Gene ID | Strain background | Direction | Details | Source | Reference |
|---|
Fungal Homologs
Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.
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| HOMOLOG ID | Species | Gene ID | Gene name | Description | Source |
|---|
External Identifiers
List of external identifiers for the protein from various database sources.
18 entries for 8 sourcesIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
Resources
Homologs
AGD | AnalogYeast | BLASTP at NCBI | FungiDB | PhylomeDB | PomBase | YGOB | YOGY
Protein Databases
AlphaFold Protein Structure | GPMDB | ModelArchive | Pfam domains | SUPERFAMILY | TopologYeast | UniProtKB
Localization
CYCLoPs | dHITS | LoQAtE | YeastGFP | YeastRC Public Images | YeastRGB | YPL+
Post-translational Modifications
CoSMoS.c. | PhosphoGRID | PhosphoPep
S288C only
BLASTN | BLASTP | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species
BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi