SUB1 / YMR039C Homology


Standard Name
SUB1 1
Systematic Name
YMR039C
SGD ID
SGD:S000004642
Aliases
TSP1
Feature Type
ORF , Verified
Description
Transcriptional regulator; facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in nonhomologous end-joining (NHEJ) of ds breaks in plasmid DNA, but not chromosomal DNA; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes; negatively regulates sporulation; protein abundance increases in response to DNA replication stress; functionally complemented by human SUB1 (PC4) 2 3 4 5 6 7
Name Description
SUppressor of TFIIB mutations 1
Comparative Info

Homologs

Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.


Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Species Gene ID Gene name Source

Functional Complementation

Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).

2 entries for 2 complements


Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

SpeciesGene IDStrain backgroundDirectionDetailsSourceReference
Homo sapiensHGNC:19985S288Cother complements yeastOverexpression of human SUB1 (PC4) in a yeast homozygous diploid sub1 null mutant complements the increase in sporulation efficiency conferred by the sub1 mutation.SGDGupta R, et al. (2015)
PMID:26147804
Homo sapiensHGNC:19985S288Cother complements yeastP-PODWang JY, et al. (2004)
PMID:15199162
Showing 1 to 2 of 2 entries

Fungal Homologs

Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.


Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Species Gene ID Gene name Description Source

External Identifiers

List of external identifiers for the protein from various database sources.

16 entries for 9 sources


Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

External IDSource
orf19.5666CGD
4696DIP
Z48502GenBank/EMBL/DDBJ
6323682GenBank/EMBL/DDBJ
1711571GenBank/EMBL/DDBJ
695719GenBank/EMBL/DDBJ
CAA88405.1GenBank/EMBL/DDBJ
4499LoQAtE
NM_001182536.1NCBI
DAA09938.1NCBI
Showing 1 to 10 of 16 entries

Resources