SUB1 / YMR039C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant displays heat sensitivity, increased mutation frequency, sensitivity to oxidative stress, abnormal phosphorylation of RNA polymerase II, and reduced tRNA levels; in large-scale studies, null mutant shows reduced competitive fitness and slow utilization of galactose; diploid homozygous null mutant shows increased chronological lifespan and sporulation efficiency, and decreased resistance to oxidative stress, UV, desiccation, and heat shock; null mutant shows altered resistance to a variety of chemicals

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources