Interaction Help

ARF2 / YDL137W Interactions

Interaction annotations are curated by BioGRID and include physical or genetic interactions observed between at least two genes. An interaction annotation is composed of the interaction type, name of the interactor, assay type (e.g., Two-Hybrid), annotation type (e.g., manual or high-throughput), and a reference. Experimental details, phenotype, modification, and multiple mutant information are included when available.


Summary
The arf2 null mutant is viable; the null mutant of paralog arf1 is viable; the arf2 arf1 double mutant is inviable.

Source: All physical and genetic interaction annotations listed in SGD are curated by BioGRID.

Genetic Interactions

An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.


Genetic Interactions

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.

Interactor Interactor Allele Assay Annotation Action Phenotype SGA score P-value Source Reference

Physical Interactions

An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.


Physical Interactions 43 entries for 36 genes

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.

InteractorAssayAnnotationActionModificationReference

Protein interactions were identified using statistically significant enrichment of the proteins in the forward and reverse pull-downs, as well as making use of the profile similarities of interacting proteins in a correlation analysis. High confidence interactions have a total score >=2. This score is a sum of the FDR score of the forward pull-down + FDR score of the reverse pull-down + correlation score.

ALD6Affinity Capture-MShigh-throughputHitNo ModificationMichaelis AC, et al. (2023) PMID:37968396
ARF1Affinity Capture-MShigh-throughputHitNo ModificationHo Y, et al. (2002) PMID:11805837
ARF1PCAhigh-throughputBaitNo ModificationTarassov K, et al. (2008) PMID:18467557

Protein interactions were identified using statistically significant enrichment of the proteins in the forward and reverse pull-downs, as well as making use of the profile similarities of interacting proteins in a correlation analysis. High confidence interactions have a total score >=2. This score is a sum of the FDR score of the forward pull-down + FDR score of the reverse pull-down + correlation score.

ARF1Affinity Capture-MShigh-throughputBaitNo ModificationMichaelis AC, et al. (2023) PMID:37968396

RNA Tagging

BFR1Affinity Capture-RNAhigh-throughputHitNo ModificationLapointe CP, et al. (2015) PMID:26524240
CAF20Affinity Capture-MShigh-throughputHitNo ModificationGay S, et al. (2018) PMID:29775579
CCR4Affinity Capture-RNAhigh-throughputHitNo ModificationMiller JE, et al. (2018) PMID:29158339
CDC5Proximity Label-MSmanually curatedHitNo ModificationZhou X, et al. (2021) PMID:33481703
FMP48Affinity Capture-MShigh-throughputHitNo ModificationHo Y, et al. (2002) PMID:11805837
GGA1Two-hybridmanually curatedHitNo ModificationZhdankina O, et al. (2001) PMID:11124697
Showing 1 to 10 of 43 entries

Interaction Network

This diagram displays physical (purple lines) and genetic (green lines) interactions between the given gene (yellow circle) and its interactors (gray circles) based on the number of experiments supporting each interaction (adjustable using the slider at the bottom). Interactions between the interactors for a given gene are also shown.


Reset

Click on a gene to go to its specific page within SGD; drag any of the gene objects around within the visualization for easier viewing; filter by interaction type (genetic or physical) using the radio buttons; click “Reset” to automatically redraw the diagram; filter the number of interactors displayed by adjusting the number of experiments supporting a gene's interaction with the given gene by clicking anywhere on the slider bar or dragging the tab to the desired filter number.

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Resources


BioGRID | CYC2008 | DIP | GeneMANIA | IMP | InterologFinder | ModelArchive | TheCellMap | YeastRC Two-Hybrid

FRQ1