ARF2 / YDL137W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutants have abnormal vacuolar morphology, decreased competitive fitness, are impaired in the use of arginine as a nitrogen source, sensitive to antimalarial mefloquine and the histone deacetylase inhibitor CG-1521, resistant to acetic acid; conditional mutants are sensitive to cold; overexpression slows vegetative growth in strain S288C, increases filamentous growth in strain Sigma1278b, arrests cell cycle progression at G2 or M phase in strain W303

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources