New & Noteworthy

Reference Genome Annotation Update R64.4

September 08, 2023

The S. cerevisiae strain S288C reference genome annotation was updated. The new genome annotation is release R64.4.1, dated 2023-08-23. Note that the underlying genome sequence itself was not altered in any way.

This annotation update included:

• new uORFs for 3 ORFs:
  • FPS1/YLL043W
  • ACC1/YNR016C
  • HOL1/YNR055C
• 8 new ncRNAs:
  • SUT035/YNCC0015W
  • SUT053/YNCD0033W
  • SUT468/YNCD0034C
  • SUT532/YNCG0047C
  • SUT125/YNCG0048W
  • SUT126/YNCG0049W
  • SUT390/YNCP0025W
  • SUT418/YNCP0026W
• 3 ORFs demoted from ‘Uncharacterized’ to ‘Dubious’ based on request from NCBI because they overlap tRNAs:
  • YDR278C
  • YOL013W-A
  • YPR108W-A

Various sequence and annotation files are available on SGD’s Downloads site. You can find more update details on the Details of 2023 Reference Genome Annotation Update R64.4 SGD Wiki page. 

Categories: Data updates

Tags: genome annotation update , Saccharomyces cerevisiae